Investigation Preliminary antimicrobial and anticancer properties: on Topic Rubia tinctorum plant by using Polydimethylsiloxane (CAR/PDMS)

Abstract

In this study, the antioxidant content in Rubia tinctorum was investigated. The extraction of essences is sensitive to operational conditions. Therefore, the effect of different extraction techniques by using HS -SPME fiber assembly Carboxen/Polydimethylsiloxane (CAR/PDMS), on the quality of essence oil composition was inspected and the composition of the final product was recognized using gas chromatography and mass spectroscopy.Essential Rubia tinctorum is widely used in pharmaceutical, sanitary, cosmetic, agriculture and food industries for their bactericidal, virucidal, fungicidal, antiparasitical and insecticidal properties. Their anticancer activity is well documented. This review is focused on the activity of essential Rubia tinctorum and their components on various types of Blood cancer cells. The chemical composition of the essential Rubia tinctorum from was analyzed by GC-MS. The main constituents were. Ocimene, Sabinene hydrate acetate, Bornyl acetate, Thymol , Methyl isoeugenol ,isoelemicin, Asarone, Neophytadiene. The cytotoxic effect of essential and extracts Rubia tinctorum were analyzed, the results showed that the substance. Good resistance against the toxicity of cell lines is shown MOLT4. Keywords: Antioxidants, Gas chromatography, Rubia tinctorum, Blood cancer cells