Peculiarities of chronic gastritis in diabetes mellitus type II

Abstract

A research objective was assessment of histological and functional features of chronic gastritis in patients with diabetes mellitus type II. 95 patients with diabetes type II underwent endoscopic study of the stomach with target biopsy, intragastric рН – metry. At morphological research in patients with diabetes mellitus type II atrophic gastritis was observed more often than superficial gastritis. The specific gravity of atrophic gastritis increases with elevated duration of diabetes, moreover, high prevalence of atrophy is observed in group of patients suffering from diabetes more than 10 years. 71,6 % of patients revealed chronic gastritis associated with Helicobacter pylori. HP-colonization in patients with diabetes type II has its features. Diabetes type II was mostly associated with high HP- colonization. Decrease in HP - colonization and frequent intestinal metaplasia are noticed with increased duration of diabetes. At increasing duration of Diabetes, reduction in the main indicators of acid production of the stomach becomes notable.