Comparison of three formulas to evaluate acute renal failure in preeclamptic puerperal women

Abstract

Introduction: Acute renal failure in puerperal women who have suffered preeclampsia and HELLP syndrome has been scarcely studied. Aim: to compare the Cockroft-Gault, Modification of Diet in Renal Disease, and Chronic Kidney Disease Epidemiology Collaboration equations with the 24 hour creatinine clearance formula in puerperal women. Materials & Methods: This was an observational study. The selected formulas were calculated at 1, 8, 16 and 24 hours after delivery. Pearson correlation and Bland-Altman tests were performed. Results: 38 patients (mean age 26.4 years) were included. The three highest correlation coefficients with the 24 h creatinine clearance were the Modification of Diet in Renal Disease at 8 hours (r² = 0.920), and the Chronic Kidney Disease Epidemiology Collaboration equation at 24 (r² = 0.847) and 16 hours (r² = 0.842) post-delivery. Conclusion: In puerperal women who have suffered preeclampsia and HELLP syndrome, the Chronic Kidney Disease Epidemiology Collaboration equation shows more consistent results the first 24 hours post-delivery.