"West Kazakhstan Marat Ospanov Medical Unversity" Repository

INNATE AND ADAPTIVE IMMUNITY STATE DETERMINATION IN CHILDREN WITH PYELONEPHRITIS ON CONGENITAL HYDRONEPHROSIS BACKGROUND IN ACTIVE STAGE OF THE DISEASE

Show simple item record

dc.contributor.author MISHYNA, M.
dc.contributor.author DAVYDENKO, V.
dc.contributor.author MARCHENKO, I.
dc.contributor.author MOZGOVA, YU.
dc.contributor.author MALANCHUK, S.
dc.contributor.author DUBOVIK, O.
dc.contributor.author MISHYN, YU.
dc.date.accessioned 2024-01-17T04:05:39Z
dc.date.available 2024-01-17T04:05:39Z
dc.date.issued 2021-04-22
dc.identifier.other DOI: 10.24412/2707-6180-2021-63-63-69
dc.identifier.uri http://localhost:8080/xmlui/handle/123456789/174
dc.description Conclusions: Thus, there is no doubt about the presence of immune mechanisms in children with pyelonephritis on congenital hydronephrosis background, autoimmune syndrome is developed by damage of own cells membranes and sensitization to cell components mimicking the infectious agent antigens. Post-infectious autoimmune syndrome in combination with secondary immunodeficiency is a more severe condition because involves not only autoaggression, but also a lack of factors and components of immune response, manifested by severe course of pyelonephritis in children with congenital hydronephrosis. The existing immunodeficiency creates conditions for disease progression, stimulates other pathogenetic factors, and as the infectious inflammatory process is developing, an immunological insufficiency is worsening and associated not only with the persistence of microorganisms, their toxins, but also with depletion of immune system reserves. ru
dc.description.abstract Conclusions: Thus, there is no doubt about the presence of immune mechanisms in children with pyelonephritis on congenital hydronephrosis background, autoimmune syndrome is developed by damage of own cells membranes and sensitization to cell components mimicking the infectious agent antigens. Post-infectious autoimmune syndrome in combination with secondary immunodeficiency is a more severe condition because involves not only autoaggression, but also a lack of factors and components of immune response, manifested by severe course of pyelonephritis in children with congenital hydronephrosis. The existing immunodeficiency creates conditions for disease progression, stimulates other pathogenetic factors, and as the infectious inflammatory process is developing, an immunological insufficiency is worsening and associated not only with the persistence of microorganisms, their toxins, but also with depletion of immune system reserves. ru
dc.language.iso en ru
dc.publisher West Kazakhstan Marat Ospanov Medical University ru
dc.subject children ru
dc.subject pyelonephritis ru
dc.subject etiological factor ru
dc.subject immunity ru
dc.subject pro-inflammatory cytokines ru
dc.subject immunoglobulins ru
dc.title INNATE AND ADAPTIVE IMMUNITY STATE DETERMINATION IN CHILDREN WITH PYELONEPHRITIS ON CONGENITAL HYDRONEPHROSIS BACKGROUND IN ACTIVE STAGE OF THE DISEASE ru
dc.type Article ru


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Browse

My Account